Significantly. Smoking reduces blood flow to the skin, depriving it of oxygen and nutrients. It also releases enzymes that break down collagen and elastin, leading to deep wrinkles around the mouth and eyes.
Yes. Higher altitudes have stronger UV radiation and lower air pressure, which can increase oxidative stress and dehydrate the skin. Sunscreen and antioxidants become even more critical.
Start with a low concentration 2-3 times per week, gradually increasing as tolerated. Oily skin often handles retinol better than dry skin, but consistency is more important than frequency.
A non-comedogenic (won't clog pores), oil-free formula that hydrates without feeling heavy or greasy. Look for ingredients like hyaluronic acid for hydration and niacinamide to soothe and refine pores.